We desperately need more Cold Warframes and we desperately need more fat women, so I would want to make a frame that is shaped from the bones of a great Sentient beast (something with whale, seal, dolphin, shark traits) with Orokin/Warframe hagfish giving it life and mobility. Sort of like Caliban, except it represents the post-war reality of Tenno and Sentient fusion. The dead Sentient, and the Orokin puppeting it's limp body.